Protein name:
Syntaxin-1A ;
Alternative:
Neuron-specific antigen HPC-1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Interacts with VAPA and SYBU. Binds STXBP6. Found in a complex with VAMP8 and SNAP23. Found in a ternary complex with STX1A and SNAP25 (By similarity). Interacts with SLC6A4 (By similarity). Binds SYTL4. Interacts with OTOF and LGI3. Interacts with SYT6 and SYT8; the interaction is Ca(2+)-dependent.
Function:
Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Subcellular Location:
Cytoplasmic vesicle
secretory vesicle
synaptic vesicle membrane
Single-pass type IV membrane protein
Cell junction
synapse
synaptosome
Protein Attributes:
50:
MKDRTQELRT | AKDSDDDDDV | TVTVDRDRFM | DEFFEQVEEI | RGFIDKIAEN |
100:
VEEVKRKHSA | ILASPNPDEK | TKEELEELMS | DIKKTANKVR | SKLKSIEQSI |
150:
EQEEGLNRSS | ADLRIRKTQH | STLSRKFVEV | MSEYNATQSD | YRERCKGRIQ |
200:
RQLEITGRTT | TSEELEDMLE | SGNPAIFASG | IIMDSSISKQ | ALSEIETRHS |
250:
EIIKLETSIR | ELHDMFMDMA | MLVESQGEMI | DRIEYNVEHA | VDYVERAVSD |
288:
TKKAVKYQSK | ARRKKIMIII | CCVILGIIIA | STIGGIFG
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
ELISA Kit for Mouse Syntaxin-1A
ELISA Kit for Mouse Syntaxin-1A
ELISA Kit for Mouse Syntaxin-1A
ELISA Kit for Mouse Syntaxin-1A
CLIA Kit for Mouse Syntaxin-1A
CLIA Kit for Mouse Syntaxin-1A
CLIA Kit for Mouse Syntaxin-1A
CLIA Kit for Mouse Syntaxin-1A
Polyclonal Antibody for Mouse Syntaxin-1A
Polyclonal Antibody for Mouse Syntaxin-1A
Polyclonal Antibody for Mouse Syntaxin-1A
Polyclonal Antibody for Mouse Syntaxin-1A
Monoclonal Antibody for Mouse Syntaxin-1A
Monoclonal Antibody for Mouse Syntaxin-1A
Monoclonal Antibody for Mouse Syntaxin-1A
Monoclonal Antibody for Mouse Syntaxin-1A
Protein for Mouse Syntaxin-1A
Protein for Mouse Syntaxin-1A
Protein for Mouse Syntaxin-1A
Protein for Mouse Syntaxin-1A
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 29-41; 47-56; 58-84; 95-108; 126-142; 152-158 AND 233-246;IDENTIFICATION BY MASS SPECTROMETRY
strain :
C57BL/6 .
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SYTL4
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH SYT6 AND SYT8
5.
"Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse."
Roux I.
,
Safieddine S.
,
Nouvian R.
,
Grati M.
,
Simmler M.-C.
,
Bahloul A.
,
Perfettini I.
,
Le Gall M.
,
Rostaing P.
,
Hamard G.
,
Triller A.
,
Avan P.
,
Moser T.
,
Petit C.
Cell127:277-289(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH OTOF
strain :
BALB/c .
tissue :
Cochlea .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;INTERACTION WITH LGI3