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Index > Protein center > Stx1a(Gene name) > Mouse
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  • Stx1a (Gene name),
  • Syntaxin-1A (Protein name ),  STX1A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Stx1a;
    Protein name:
    Syntaxin-1A;
    Alternative:
    Neuron-specific antigen HPC-1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Interacts with VAPA and SYBU. Binds STXBP6. Found in a complex with VAMP8 and SNAP23. Found in a ternary complex with STX1A and SNAP25 (By similarity). Interacts with SLC6A4 (By similarity). Binds SYTL4. Interacts with OTOF and LGI3. Interacts with SYT6 and SYT8; the interaction is Ca(2+)-dependent.
    Function:
    Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
    Subcellular Location:
    Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane Single-pass type IV membrane protein Cell junction synapse synaptosome
    Protein Attributes:
    Sequence length:
    288
    Sequence:
    50:
    MKDRTQELRT | AKDSDDDDDV | TVTVDRDRFM | DEFFEQVEEI | RGFIDKIAEN | 
    100:
    VEEVKRKHSA | ILASPNPDEK | TKEELEELMS | DIKKTANKVR | SKLKSIEQSI | 
    150:
    EQEEGLNRSS | ADLRIRKTQH | STLSRKFVEV | MSEYNATQSD | YRERCKGRIQ | 
    200:
    RQLEITGRTT | TSEELEDMLE | SGNPAIFASG | IIMDSSISKQ | ALSEIETRHS | 
    250:
    EIIKLETSIR | ELHDMFMDMA | MLVESQGEMI | DRIEYNVEHA | VDYVERAVSD | 
    288:
    TKKAVKYQSK | ARRKKIMIII | CCVILGIIIA | STIGGIFG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Syntaxin-1A
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    E1124h
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    96T
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    ELISA Kit for Mouse Syntaxin-1A
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    E1124r
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    ELISA Kit for Mouse Syntaxin-1A
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    E1124b
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    96T
    ELISA Kit for Mouse Syntaxin-1A
    Cat.:
    E1124m
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    Packing:
    96T
    CLIA Kit for Mouse Syntaxin-1A
    Cat.:
    U1124r
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    Packing:
    96T
    CLIA Kit for Mouse Syntaxin-1A
    Cat.:
    U1124h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Syntaxin-1A
    Cat.:
    U1124m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Syntaxin-1A
    Cat.:
    U1124b
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Syntaxin-1A
    Cat.:
    P1124Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Syntaxin-1A
    Polyclonal Antibody for Mouse Syntaxin-1A
    Cat.:
    P1124Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Syntaxin-1A
    Cat.:
    P1124Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Syntaxin-1A
    Monoclonal Antibody for Mouse Syntaxin-1A
    Monoclonal Antibody for Mouse Syntaxin-1A
    Monoclonal Antibody for Mouse Syntaxin-1A
    Protein for Mouse Syntaxin-1A
    Protein for Mouse Syntaxin-1A
    Protein for Mouse Syntaxin-1A
    Protein for Mouse Syntaxin-1A

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    References
    1. 1.
      Fujiwara T. , Genda M. , Nagai A. , Okazaki M. , Watanabe T. , Nagamatsu S. , Akagawa K.
      Submitted (2001-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      Lubec G. , Kang S.U.
      Submitted (2007-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-41; 47-56; 58-84; 95-108; 126-142; 152-158 AND 233-246;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      tissue: Brain.
    3. 3.
      "Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a."
      Torii S. , Zhao S. , Yi Z. , Takeuchi T. , Izumi T.
      Mol. Cell. Biol.22:5518-5526(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SYTL4
    4. 4.
      "Synaptotagmin VI and VIII and syntaxin 2 are essential for the mouse sperm acrosome reaction."
      Hutt D.M. , Baltz J.M. , Ngsee J.K.
      J. Biol. Chem.280:20197-20203(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SYT6 AND SYT8
    5. 5.
      "Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse."
      Roux I. , Safieddine S. , Nouvian R. , Grati M. , Simmler M.-C. , Bahloul A. , Perfettini I. , Le Gall M. , Rostaing P. , Hamard G. , Triller A. , Avan P. , Moser T. , Petit C.
      Cell127:277-289(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH OTOF
      strain: BALB/c.
      tissue: Cochlea.
    6. 6.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    7. 7.
      "Leucine-rich glioma inactivated 3 associates with syntaxin 1."
      Park W.-J. , Lee S.E. , Kwon N.S. , Baek K.J. , Kim D.-S. , Yun H.-Y.
      Neurosci. Lett.444:240-244(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH LGI3
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